Active

Contract Opportunity

Procurement Technical Assistance Centers (PTACs) are an official government contracting resource for small businesses. Find your local PTAC (opens in new window) for free government expertise related to contract opportunities.

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.

(ii) The solicitation number is 75N95023Q00261 and the solicitation is issued as a request for quotation (RFQ).

This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; FAR Subpart 13.5— Simplified Procedures for Certain Commercial Items; and FAR Part 12—Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2023-02, with effective date March 16, 2023.

(iv) The associated NAICS code 334516 - Analytical Laboratory Instrument Manufacturing and the small business size standard is 1,000 employees. This requirement is Brand Name or Equal, full and open competition.

(v) This requirement is for the following items:

10X Genomics or equal High-throughput In Situ Instrument

Description: Cat no: Quantity

Xenium Analyzer 1000481 1.00

Vibration Isolation Table 1000531 1.00

shipping n/a 1.00

(vi) Instrument must include these specifications:

• Enable simultaneous detection of RNA and protein within the same tissue section.


• Compatible with custom, pre-validated reagent panels that work off-the-shelf and can be customized with additional targets.


• Probe chemistry with dual hybridization and ligation stringency enabling targeting of expressed SNPs and isoforms.


• Nondestructive workflow, allowing for the same section to be H&E or IF stained post-workflow.


• Allows for up to 3 runs per week with up to 2 slides per run, accommodating up to 10 x 20 mm tissue per slide.


• Concurrent onboard analysis capabilities process image data, localize RNA signal, and perform secondary analysis- including cell segmentation, transcript assignment to cells, clustering, and differential expression results.


• Ability to localize detected transcripts with sub-50 nm resolution in the XY plane.


• Three-dimensional acquisition of spatial information via Z-stacking with a 0.75 um step size across the whole tissue thickness


• Comprehensive and intuitive software to analyze and interpret acquired data locally or in a cloud platform


• Fully portable data with open standard file formats including: MEX, HDF5, Zarr for cell -feature matrices; Zarr, CSV, and Parquet for transcripts and segmentation boundaries; and OME.TIFF for images


• Detection of up to 400 RNA transcripts at subcellular resolution and designed for an increased plexy detection of up to 1,000 analytes simultaneously in the future


• Compatible with fresh frozen and formalin-fixed, paraffin-embedded tissues samples


• Baseline optical resolution is ~0.2 microns/pixel which allows us to localize detected transcripts in a single image to
  

(vii) The Government anticipates award of a firm fixed-price purchase order for this acquisition, and the anticipated delivery date is 6 months after receipt of order (ARO). Delivery will be f.o.b. destination. The place of delivery and acceptance will be 9000 Rockville Pike; Bldg. T44, Bethesda, MD 20892.

(viii) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far

https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html

(End of provision)

The following provisions apply to this acquisition and are incorporated by reference:

• FAR 52.204-7, System for Award Management (Oct 2018)


• FAR 52.204-16, Commercial and Government Entity Code Reporting (Aug 2020)


• FAR 52.211-6, Brand Name or Equal (Aug 1999)


• FAR 52.212-1, Instructions to Offerors-Commercial Items (Mar 2023)


• FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Dec 2022)


• FAR 52.225-6, Trade Agreements Certificate (Feb 2021)


• HHSAR 352.239-73, Electronic and Information Technology Accessibility Notice (December 18, 2015)

The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses:

https://www.acquisition.gov/browse/index/far

https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html

(End of clause)

The following clauses apply to this acquisition and are incorporated by reference:

• FAR 52.204-13, System for Award Management Maintenance (Oct 2018)


• FAR 52.204-18, Commercial and Government Entity Code Maintenance (Aug 2020)


• FAR 52.212-4, Contract Terms and Conditions--Commercial Items (Dec 2022). Addendum to this FAR clause applies to this acquisition and is attached.


• HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015)


• HHSAR 352.239-74, Electronic and Information Technology Accessibility (December 18, 2015)

The following provisions and clauses apply to this acquisition and are attached in full text. Offerors MUST complete the provisions at 52.204-24 and 52.204-26 and submit completed copies as separate documents with their proposal.

• FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Nov 2021)


• FAR 52.204-26 Covered Telecommunications Equipment or Services-Representation (Oct 2020)


• FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders--Commercial Items (Mar 2023)


• NIH Invoice and Payment Provisions

(ix) The Government will evaluate quotations or offers in accordance with FAR 13.106-2 and award a purchase order from this solicitation to the responsible offeror whose quote conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotes:

a. Technical capability of the item offered to meet the Government requirement;

b. Price; and

c. Past performance [see FAR 13.106-2(b)(3)].

Technical and past performance, when combined, are (1) significantly more important than cost or price

A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.

(x) The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items (Nov 2021), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer.

(xi) The clause at FAR 52.212-4, Contract Terms and Conditions-Commercial Items (Dec 2022), applies to this acquisition. Addendum to this FAR clause applies to this acquisition and is attached.

(xii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition.

(xiii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.

(xiv) Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include: past performance, special features required for effective program performance, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, and environmental and energy efficiency considerations.

Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order.

The Unique Entity ID from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All quotations must be received by 11:00 A.M. Eastern, on June 8, 2023, and reference Solicitation Number 75N95023Q00261. Responses must be submitted electronically to Hashim Dasti, Contract Specialist, at hashim.dasti@nih.gov and Karen Mahon, Contracting Officer, at karen.mahon@nih.gov.

Fax responses will not be accepted.

Attachments/Links