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PRE-SOLICITATION NOTICE – NOTICE OF INTENT

NOI-NIAID-2163832

NAICS – 518210, Data Processing, Hosted and Related

This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Weather Source, LLC of Salem, NH to procure a dataset deliverable, in tabular and shapefile format, on past and forecasted weather and climatology data to be used to predict Nontuberculous Mycobacteria (NTM) infection and disease rates. This data will be used for spatial analysis and modeling in support of multiple ongoing projects in the Laboratory of Clinical Immunology and Microbiology (LCIM), Epidemiology and Population Studies Unit (EPSU).

The National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases NIAID), Laboratory of Clinical Immunology and Microbiology (LCIM), has within it the Epidemiology and Population Studies Unit (EPSU) which leads population-based and clinical epidemiologic research on mycobacterial, viral, fungal, and parasitic conditions with a strong emphasis on the study of Nontuberculous mycobacteria (NTM) and bronchiectasis. The unit leverages a broad array of epidemiological methods: Disease burden studies using national morbidity and mortality datasets (hospital discharge datasets, Medicare, Electronic Medical Records, registries) , as well as population-based data from integrated health care systems (HMOs); Multivariable modeling, e.g. integrated analysis of observational cohorts with clinical and microbiologic data to identify relative host and pathogen contributions to infection and disease, including molecular and genetic markers of disease susceptibility and progression; Geospatial models to identify disease clustering and environmental predictors of disease; Machine learning; and Household transmission studies. Using these methods, the Epidemiology and Population Studies Unit conducts pre- and post-licensure vaccine evaluation; defines optimal clinical endpoints for clinical trials of vaccines or new therapeutics; evaluates data underlying science-to-policy issues; designs clinical and population-based studies; develops and tests hypotheses regarding disease prevalence, trends, and risk factors; develops “electronic phenotypes” and clinical algorithms for selected infectious diseases. The purpose of this acquisition is to procure a dataset deliverable, in tabular and shapefile formats, on weather and climate data to be used to predict NTM infection and disease rates for spatial analyses and modeling, in support of multiple ongoing projects in the EPSU.

The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide comparable services may submit a capability statement that will be considered by email (subject line to reference NOI-NIAID-2163832) to Dana Monroe at dana.monroe@nih.gov, by 5:00pm eastern daylight savings time Sunday, March 26, 2023. All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.