ICell DopaNeurons and ICell GlutaNeurons
Agency: | |
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Level of Government: | Federal |
Category: |
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Opps ID: | NBD00159289869869757 |
Posted Date: | Mar 14, 2024 |
Due Date: | Mar 19, 2024 |
Source: | https://sam.gov/opp/5dbffdfe2b... |
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- Contract Opportunity Type: Presolicitation (Original)
- All Dates/Times are: (UTC-04:00) EASTERN STANDARD TIME, NEW YORK, USA
- Original Published Date: Mar 14, 2024 10:47 am EDT
- Original Response Date: Mar 19, 2024 12:00 pm EDT
- Inactive Policy: Manual
- Original Inactive Date: Mar 20, 2024
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Initiative:
- None
- Original Set Aside:
- Product Service Code: 6505 - DRUGS AND BIOLOGICALS
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NAICS Code:
- 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
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Place of Performance:
Rockville , MDUSA
The National Center for Advancing Translational Sciences (NCATS) is a part of the NIH, with a mission to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. A significant emphasis of NCATS is the rapid development of effective therapies for patients diagnosed with these conditions. NCATS is directly addressing this problem by discovering new technologies and other approaches that could significantly accelerate the process of developing and
deploying solutions that all translational researchers can use. iCell Dopa and Gluta Neurons are iPS cell-derived human midbrain floorplate dopaminergic and glutamatergic neurons respectively, differentiated in protocols licensed and adapted from the Lorenz Studer lab (Memorial Sloan Kettering) and industrialized for scale at FCDI. They are fully differentiated, >70% pure midbrain neurons, expressed relevant neuronal markers. These neurons are appropriate for electrophysiological testing invitro also compatible to wide range of biochemical and cell-based assays like cell viability, cell mitophagy, calcium signaling, neurites outgrowth. The objective of this procurements is to use these iPSC derived human mature neurons in 3D invitro circuitry model to get in vivo relevance interims of morphology, network formation and mainly functionality in pharmacological assays.
- c/o 3WFN MSC 6012 301 N Stonestreet Ave
- Bethesda , MD 20892
- USA
- Chandani Hangilipola
- chandani.hangilipola@nih.gov
- Phone Number 13014807089
- Mar 14, 2024 10:47 am EDTPresolicitation (Original)
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